RNA-protein interactions in infection
Our research lab “Molecular Infection Biology” is part of the IRI Life Sciences at the Humboldt University Berlin (Germany).
The group is working on molecular infection biology to understand the interaction of pathogenic bacteria and their host cells. We are mainly interested in RNA-protein interactions during infection. Head over to our Projects to learn more about our research.
In our lab, we are investigating RNA-protein interactions. We recently developed a novel purification technique ( PTex ) which enables us to purify RNA-protein complexes from any biological source. We are using PTex to study post-transcriptional regulation of human cells which are infected with pathogenic bacteria. In our model organism Salmonella Typhimurium, we particularly look at extracellular vesicles and how the bacterium uses these to deliver RNA and proteins to host cells during infection.
When not at the bench, we play Pandemic Legacy. Or we do the Journal Club in a pub…
PTex is a new method to purify UV-cross-linked RNA-protein complexes from any biological source.